See these 10 great ways at http://home.howstuffworks.com/10-ways-to-organize-home-office.htm to organize your home office.
Here is a quick summary for you:
- Get an organizational system in place
- Sweep your desk clean
- Interior design your filing cabinet
- Toss it
- Curb cable clutter
- Keep important accessories handy
- Move office equipment off your desk
- Relocate personal items
- Rein in your calendar and to-do lists
- Organize your PC